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全國(guó)統一銷售(shòu)熱綫：活(huó)體(tǐ)轉(zhuǎn)基(jī)因--卡(qiǎ)鉗電(diàn)極(jí)用於(yú)體(tǐ)內肌肉基因/藥物傳遞電(diàn)極(jí).BTX Caliper 電極是(shì)一(yī)種(zhǒng)體(tǐ)內(nèi)可(kě)復用的(dí)卡鉗狀(zhuàng)測徑(jìng)器(qì)電極，有多種(zhǒng)應用，如(rú)在體(tǐ)內進(jìn)行基因(yīn)和(hé)藥(yào)物(wù)的傳(chuán)遞，也可(kě)經皮(pí)膚應用(yòng)及在(zài)完整(zhěng)的(dí)植(zhí)物上(shàng)應用(yòng)。
活體(tǐ)轉(zhuǎn)基因--卡(qiǎ)鉗(qián)電極(jí)384L 用於(yú)體內肌(jī)肉(ròu)基因/藥物傳遞電(diàn)極
BTX Caliper電極是一種體(tǐ)內可復用的卡鉗狀(zhuàng)測徑(jìng)器電(diàn)極(jí)，有多(duō)種(zhǒng)應用，如在體內進行基因(yīn)和(hé)藥(yào)物的傳(chuán)遞(dì)，也(yě)可經皮膚應用及(jí)在(zài)完(wán)整(zhěng)的植物上(shàng)應(yīng)用。該電(diàn)極由一(yī)個(gè)測(cè)徑(jìng)器(qì)和一(yī)對末端電極組(zǔ)成(chéng)，共(gòng)有兩(liǎng)種類型(xíng)：45-0101型的(dí)末端(duān)為一(yī)對(duì)1x1cm黃(huáng)銅製(zhì)末(mò)端(duān)電極，適用(yòng)於小動物，45-0102型的末端為一(yī)對1.5x1.5cm或2x2cm的(dí)不(bù)鏽鋼製末(mò)端(duān)電極，適(shì)用(yòng)於較大的(dí)區域表(biǎo)麵(miàn)，兩電(diàn)極間(jiān)的距離可(kě)以調節。
活(huó)體轉(zhuǎn)基因當(dāng)把感興趣的分子注(zhù)射(shè)到(dào)體(tǐ)內(nèi)以後，用電極板夾(jiā)住相關目標(biāo)組織，然後(hòu)給出(chū)電脈(mài)衝，電場通過(guò)電(diàn)極(jí)在組(zǔ)織細(xì)胞間形成暫(zàn)時的(dí)孔道(dào)，使分(fēn)子進入到(dào)與(yǔ)電(diàn)極(jí)接(jiē)觸的(dí)組織(zhī)細(xì)胞(bāo)內(nèi)。
The BTX Caliper Electrodes are in vivostyle re-usable electrodes that are used for a variety ofapplications. Caliper Electrodes come in two models, with eachmodel consisting of a caliper and a pair of end plates. Model 384are used for smaller animals with a smaller surface area, whilemodel 384L is used to target slightly larger surface areas. The endplates of the Caliper Electrode may be adjusted by using the blackroller mounted on the caliper. Caliper Electrodes may be cleanedwith a mild detergent and sterilized with ethanol or ethyleneoxide. Properly maintained Caliper Electrodes have an unlimitedlife, and are compatible with most BTX Electroporation Systems.
活體(tǐ)轉基因(yīn)Applications
Caliper Electrodes may be used for many electroporationapplications, including drug and gene delivery. The electrodes spanthe target area following injection of the molecule of interest,and electroporation pulses are delivered using a BTXElectroporation System, such as the ECM 600, ECM 630, ECM 830, ECM2001, or T820. The electric field introduced by the CaliperElectrodes cause transient pores to form in the cells of thetissue, allowing uptake of the molecules into the cells.Prud''Homme et al. used the Caliper electrodes to deliver plasmidDNA to skin for gene therapy studies on diabetes.1 Mir et al. usedthe Caliper Electrode for in vivo skeletal muscle work2 as well assubcutaneous tumor electrochemotherapy applications3. CaliperElectrodes can potentially be used for intact plant work aswell.4
Caliper Electrodes complement BTX Tweezertrodes Model 520, 522; BTXGenetrodes Model 508(S) and 510(S); and BTX 2 Needle ArrayElectrodes Model 530, 531, 532, 533 as part of the BTX in vivoelectrode line. Caliper Electrodes can be used to reproduceapplications requiring Tweezertrodes (transdermal) andGenetrodes/2-Needle.
Technical Specifications
Standard Capabilities
Voltage Range: 0-500V DC(depending on electrode gap)
Pulse Length Range: 1mses-10msec
Pulse Number Range: 1-99 (depending on voltage)
Physical Characteristics
Model 384 Electrode Dimensions: 1.0cm x 1.0cm
Model 384L Electrode Dimensions: 2.0cm x 2.0cm (1.5cm x 1.5cmspare pair included)
Electrode Material: Stainless Steel
Generator Compatibility: ECM 830, 600, 630, 2001, T820
Electrode gap: 0.1-13cm
Ordering Information
System Model Available Configurations
384 Caliper Electrodes, 1.0cm x 1.0cm Brass Plates
384L Caliper Electrodes, 2.0cm x 2.0cm Stainless Steel Plates(1.5cm x 1.5cm spare pair included)
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